Our bodies host trillions of microbes, a collection of bacteria, fungi,
and protozoa that starts developing at birth and is unique to each of us. These
microorganisms can communicate with our brains to regulate bodily functions and
even influence our mood, as well as chronic conditions such as anxiety, through
chemical communication pathways known as the gut-brain axis. some those
communication means are mentioned below
VIAÂ BLOODSTREAMÂ ANDÂ NERVES
Chemicals released by microbes into nerves or the bloodstream
influence brain areas that deal with memory. Chemicals in the bloodstream can
also signal the limbic system—a brain area that processes emotion and stress—to
change our moods.
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THROUGH THE VAGUS NERVE
Sensory neurons receive chemical signals from gut microbes and
relay them up this primary signaling path between gut and brain. The brain
sends back signals that modify function, such as tempering an inflammatory response
so the gut will keep working even if a person is sick
                                     USING THE "SECOND BRAIN"

Microbes can bypass communicating with the brain and directly
signal the enteric nervous system—a meshlike network of neurons in the
digestive tract, sometimes called the second brain—to independently influence
gut movements and secretions
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